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Reinhard Klingel Selected Research

Hyperlipoproteinemias

8/2019Real-world study: Escalating targeted lipid-lowering treatment with PCSK9-inhibitors and lipoprotein apheresis.
3/2017Prevention of cardiovascular complications in patients with Lp(a)-hyperlipoproteinemia and progressive cardiovascular disease by long-term lipoprotein apheresis according to German national guidelines.
3/2017Lipoprotein(a)-hyperlipoproteinemia as cause of chronic spinal cord ischemia resulting in progressive myelopathy - successful treatment with lipoprotein apheresis.
1/2016Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization.
5/2015Lipoprotein apheresis for Lp(a)-hyperlipoproteinemia with progressive cardiovascular disease--Additional particular aspects of the Pro(a)LiFe multicenter trial.
5/2015Efficacy, safety, and tolerability of long-term lipoprotein apheresis in patients with LDL- or Lp(a) hyperlipoproteinemia: Findings gathered from more than 36,000 treatments at one center in Germany.
4/2015Lipoprotein apheresis results in plaque stabilization and prevention of cardiovascular events: comments on the prospective Pro(a)LiFe study.
4/2015Clinical benefit of long-term lipoprotein apheresis in patients with severe hypercholesterolemia or Lp(a)-hyperlipoproteinemia with progressive cardiovascular disease.
12/2013Lipoprotein apheresis in patients with maximally tolerated lipid-lowering therapy, lipoprotein(a)-hyperlipoproteinemia, and progressive cardiovascular disease: prospective observational multicenter study.
6/2003Differential indication of lipoprotein apheresis during pregnancy.

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Reinhard Klingel Research Topics

Disease

10Hyperlipoproteinemias
08/2019 - 06/2003
9Cardiovascular Diseases (Cardiovascular Disease)
12/2019 - 12/2013
5Homozygous Familial Hypercholesterolemia
03/2021 - 06/2003
4Hypercholesterolemia
12/2020 - 04/2015
4Multiple Sclerosis
01/2018 - 12/2009
3Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
12/2020 - 06/2003
2Chronic Kidney Failure (Chronic Renal Failure)
09/2020 - 01/2004
2Coronary Artery Disease (Coronary Atherosclerosis)
12/2019 - 04/2009
2Neurologic Manifestations (Neurological Manifestations)
01/2013 - 12/2009
2Drug-Related Side Effects and Adverse Reactions
01/2013 - 12/2009
2Sensorineural Hearing Loss
12/2009 - 10/2005
2Macular Degeneration (Age-Related Maculopathy)
10/2005 - 08/2002
1COVID-19
03/2021
1Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
09/2020
1Hypertriglyceridemia
01/2020
1Neuromyelitis Optica (Devic's Disease)
01/2018
1Encephalitis (Encephalitis, Rasmussen)
11/2017
1Vascular Diseases (Vascular Disease)
03/2017
1Quadriplegia (Spastic Quadriplegia)
03/2017
1Spinal Cord Ischemia
03/2017
1Spinal Cord Diseases
03/2017
1Nervous System Diseases (Neurological Disorders)
01/2013
1Ischemic Stroke
11/2012
1Pathologic Constriction (Stenosis)
11/2012
1Atherosclerotic Plaque (Atheroma)
11/2012
1Neuritis (Polyneuritis)
04/2012
1Optic Neuritis (Retrobulbar Neuritis)
04/2012
1Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
01/2011
1Hearing Loss (Hearing Impairment)
12/2009
1Thrombosis (Thrombus)
12/2009
1Atherosclerosis
12/2009
1Guillain-Barre Syndrome
12/2009
1Spondylitis
01/2009
1Rheumatoid Arthritis
01/2009
1Sudden Hearing Loss (Sudden Deafness)
09/2008
1Inflammation (Inflammations)
09/2008
1Hemorrhage
09/2008
1Ulcerative Colitis
09/2007
1Thrombocytopenia (Thrombopenia)
01/2004
1Body Weight (Weight, Body)
01/2004
1Diabetes Mellitus
01/2004

Drug/Important Bio-Agent (IBA)

14Lipoproteins (Lipoprotein)IBA
03/2021 - 06/2003
11oxidized low density lipoproteinIBA
12/2020 - 06/2003
8LipidsIBA
12/2020 - 01/2004
7Lipoprotein(a)IBA
08/2019 - 04/2009
6LDL CholesterolIBA
06/2020 - 04/2015
4SteroidsIBA
09/2020 - 12/2009
4Tryptophan (L-Tryptophan)FDA Link
01/2018 - 01/2009
3Pharmaceutical PreparationsIBA
01/2018 - 12/2009
3LDL Lipoproteins (beta Lipoproteins)IBA
04/2015 - 06/2003
2Adrenal Cortex Hormones (Corticosteroids)IBA
04/2012 - 01/2011
2Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2004 - 01/2004
2Enoxaparin (Lovenox)FDA LinkGeneric
01/2004 - 01/2004
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
12/2019
1PCSK9 InhibitorsIBA
12/2019
1AntibodiesIBA
08/2019
1AutoantibodiesIBA
11/2017
1omega-Chloroacetophenone (Mace)IBA
03/2017
1Protein Isoforms (Isoforms)IBA
01/2016
1Apoprotein(a) (Apolipoprotein (a))IBA
01/2016
1Apolipoproteins AIBA
01/2016
1Intravenous Immunoglobulins (IVIG)FDA Link
01/2011
1Infliximab (Remicade)FDA Link
01/2009
1Methotrexate (Mexate)FDA LinkGeneric
01/2009
1Proteins (Proteins, Gene)FDA Link
09/2008
1Fibrinogen (Factor I)FDA Link
10/2005
1Heparin (Liquaemin)FDA LinkGeneric
01/2004
1AldosteroneIBA
01/2004

Therapy/Procedure

24Blood Component Removal (Apheresis)
03/2021 - 08/2002
11Therapeutics
12/2020 - 06/2003
4Plasma Exchange
09/2020 - 01/2011
3Drug Therapy (Chemotherapy)
01/2018 - 06/2003
1Plasmapheresis
01/2020
1Wheelchairs (Wheel Chair)
03/2017
1Nursing Care
03/2017
1Renal Dialysis (Hemodialysis)
01/2004